Clinical Research Unit

Clinical Research Unit

Director: Wilson Miller, MD, PhD
Associate Director: Sarit Assouline, MD
Program Coordinator: Adele Cascini, BA
Nurse Manager: Vida Stibernik, RN, BScN

The Clinical Research Unit (CRU) conducts clinical trials, with a focus on hematology/oncology, and receives patients from both McGill-affiliated hospitals and hospitals throughout Québec.

The CRU has an established track record in novel cancer therapeutics, concentrating on Phase I and early Phase II development. It has performed “first in human” trials for novel targeted agents developed by companies in Canada and the US, as well as for one agent developed in a McGill research laboratory. The CRU has expertise in pharmacokinetic and pharmacodynamic studies, with the ability to prepare patient samples for molecular analyses in McGill and in outside laboratories. Clinical research from the CRU has been published in over 25 peer-reviewed manuscripts and abstracts in the last five years.

Closely tied to the Lady Davis Institute for Medical Research and the McGill Centre for Translational Research in Cancer/Montreal Centre for Experimental Therapeutics in Cancer (MCTRC/MCETC), the Unit provides the opportunity for translational medical research, linking innovative work at the laboratory bench to clinical experience at the bedside. The CRU plays an essential role in the mission of the MCTRC/MCETC to bring cancer research from basic science laboratories into the cancer clinic.

The CRU is furnished with state-of-the-art equipment, including a dedicated four-bed patient area, an additional single patient room and an adjacent nursing station for the continuous monitoring of patients. Patient treatment, follow-up and care take place in the clinic, with 24-hour nursing if necessary.

Investigations carried out in the CRU are approved and monitored by the Research Ethics Office of the Sir Mortimer B. Davis-Jewish GeneralHospital and the McGill Institutional Review Board. Policies and procedures are in place to adhere to the legislation of HealthCanadaand the US Food and Drug Administration; preparation for study activation is highly efficient. The CRU has undergone a number of rigorous external audits, always achieving outstanding evaluations.


Research Nurse CliniciansClinical Research Associates
Véronique Baril, RN, BScNRobert Zakarian, MSc
Rita Bartolucci, RN, BScNEffie Cocolakis, PhD
Susan Bescec, RN, BScNBorislav Angiozov, BSc, MA
Emilie Gravel, RNAnnie Hurtubise, PhD
Administrative AssistantNessrine Hanna, MSc
Sabrina NichiloSusan McNamara, PhD

Further information about the clinical research unit and research protocols can be found on the  Shirley and Max Konigsberg & Family Clinical Research Unit website.


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