Medical Grand Rounds

MEDICAL GRAND ROUNDS 2018-2019

The Medical Grand Rounds are an accredited group learning activity as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.

JEWISH GENERAL HOSPITAL
DEPARTMENT OF MEDICINE
MONDAY MEDICAL GRAND ROUNDS
12:30 - 1:30 PM
BLOCK AMPHITHEATRE

September 17, 2018

IT'S NEITHER BENIGN NOR MALIGNANT, IT'S NIFTP: RECENT UPDATES IN THE CLASSIFICATION OF THYROID TUMORS

Marc Philippe Pusztaszeri, MD
Associate Professor of Pathology, McGill University
Staff Member, Department of Pathology 
Jewish General Hospital 

Educational Objectives:
1. To be familiar with the most common types of thyroid neoplasms and the way they are diagnosed
2. To be familiar with the new entity NIFTP
3. To understand the impact of NIFTP on the diagnosis and management of patients with thyroid nodules 
Contact Person:  Alan Spatz, MD, Chief, Department of Pathology, Tel. 514-340-8274.

September 24, 2018

NO MEDICAL ROUNDS - SPECIAL EVENT FOR THE DEPARTMENT OF MEDICINE MEDICAL DOCTORS ONLY

*October 1, 2018

FOURTH ANNUAL DEPARTMENT OF MEDICINE CLINICAL RESEARCH SYMPOSIUM

I. QUALITY IMPROVEMENT AT THE JGH

Blair Schwartz, MDCM, MHS, FRCPC
Assistant Professor, McGill University
Division of General Internal Medicine
Department of Medicine
Department of Adult Critical Care
Jewish General Hospital

Educational Objectives:
1. To explore the nature of quality improvement research 
2. To review findings of QI work at the JGH 

II. EFFECT OF A PCSK9 NEUTRALIZING ANTIBODY ON CD36 DEGRADATION AND HEPATIC STEATOSIS IN A TRANSLATIONAL MOUSE MODEL

Morris Schweitzer PhD, MD, FRCP(C)
Associate Professor, Faculty of Medicine, McGill University
Director, Lipid Research and Management Clinic
Co-Director, Centre for Vascular Prevention
Staff, Division of Endocrinology
Jewish General Hospital

Educational Objectives: 
1. Understand the importance of CD36 in regulating the uptake of fatty acids in the liver
2. Understand the role of PCSK9 in inducing CD36 degradation in the liver
3. Understand how a PCSK9 neutralizing antibody can affect hepatic steatosis in a translational mouse model 

III. INNATE IMMUNE RESPONSE TO VACCINES AND VACCINE ADJUVANTS DELIVERED INTRAMUSCULARLY: DEFINING THE ROLE OF SKELETAL MUSCLE MYOCYTES

Gerasimos J. Zaharatos, MD, FRCPC
Assistant Professor of Medicine, McGill University
Chief, Division of Medical Microbiology
OPTILAB Montreal - MUHC
Division of Infectious Diseases, Jewish General Hospital

Educational Objectives: 
1. Provide an update of innate immune sensing pathways for pathogen-associated molecular patterns including pathogen-derived DNA and RNA
2. Review local immune responses in vaccine and vaccine adjuvant-injected muscle
3. Describe the cytosolic DNA sensing pathway in a skeletal muscle myocyte model 
Contact Person: E. L. Schiffrin, MD, PhD, Physician-in-Chief, Department of Medicine, Tel. 514-340-7538.

October 8, 2018

No Rounds - Thanksgiving

*October 15, 2018

ATOPIC DISEASE

Emma Guttman-Yassky, MD, PhD 
Sol and Clara Kest Professor of Dermatology
Vice Chair for Research, Department of Dermatology 
Director of the Center for Excellence in Eczema
Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine, Mount Sinai Medical Center, New York

Educational Objectives: 
1. Understand immune mechanisms underlying atopic dermatitis
2. Understand the mechanistic basis of the therapeutic developments in atopic dermatitis 
Contact Person: Robin Billick, MD, Chief, Division of Dermatology, Tel. 514-340-8222 ext. 5065.

*October 22, 2018

HOW TO DIE YOUNG AT A VERY OLD AGE

Nir Barzilai, MD
Professor of Medicine, Division of Endocrinology
Director, Institute for Aging Research Albert Einstein College of Medicine
Director, Nathan Shock Center of Excellence in Basic Biology of Aging
Ingeborg and Ira Leon Rennert Chair of Aging Research

Educational Objectives: 
1. Define the role of biology of aging in the onset of age-related diseases
2. Understand that aging can be targeted and prevent a variety of age-related diseases
3. Appreciate the strategy of changing the regulation (FDA etc..) for targeting aging
Contact Person: José Morais, MD, Chief, Division of Geriatric Medicine, Tel. 514-340-7501. 

*October 29, 2018

TELE-PULMONARY REHABILITATION: DOES OFFERING A HEALTHCARE SERVICE VIA TELE-MEDICINE WORK?

Nathalie Saad, MD
Assistant Professor of Medicine
McGill University 
Division of Pulmonary Medicine
Jewish General Hospital

Educational Objectives: 
1. To understand how tele-pulmonary rehabilitation improves accessibility to services 
2. To understand the impact of the tele-pulmonary rehabilitation program on patient’s health
3. To discuss the barriers to the development of a tele-medicine program in Quebec 
Contact Person: Carmela Pepe, MD, Division of Pulmonary Medicine, Tel. 514-340-8222 ext. 23636. 

*November 5, 2018

CANADIAN PATIENT SAFETY WEEK
MEDICATION MANAGEMENT AND PATIENT SAFETY: WHAT YOU NEED TO KNOW

Eva Cohen: B. Pharm., D.P.H.
Director of Pharmacy
Ryan Kerzner, B. Pharm., M. Sc.
Pharmacist
& Gaelle Abittan B. Pharm., M. Sc.
Assistant Director of Pharmacy

Educational Objectives: 
1. Review Medication Management Accreditation Standards
2. JASPRO: Role of Antimicrobial Stewardship Program
3. Understand clinical pertinence of medication reconciliation and strategies currently in place to achieve standards
Contact Person: Chantal Bellerose,  Dt. P., B. Sc., M. Sc. Health Adm., Assistant to DGA -Director, Director DQEPEA and Coordinator of quality, risk management, accreditation, clinical ethics and user experience, ext. 27895. 

*November 12, 2018

MYELOPROLIFERATIVE NEOPLASM: 2018 UPDATE ON DIAGNOSIS AND MANAGEMENT

Shireen Sirhan, MD
Assistant Professor of Medicine
McGill University
Member, Division of Hematology
Jewish General Hospital

Educational Objectives:
1. 2016 WHO revision of MPN diagnostic criteria and its practical implications 
2. Diagnostic algorithms for Essential Thrombocytosis and Polycythemia Vera 
3. Overview of Current and future Therapies 
4. Overview of Practical Management issues with new therapies 
Contact Person: Hans Knecht, MD, Chief, Division of Hematology, Tel 514-340-8222 ext. 28799.

*November 19, 2018

THE ROLE OF PSYCHOSOCIAL DETERMINANTS IN QUALITY OF LIFE (QoL) IN INFLAMMATORY BOWEL DISEASE - MOVING TOWARDS A POSITIVE PARADIGM

Gary E. Wild, MDCM, PhD, M. Sc. (Health Psychology), FRCPC
Grad. Cert. Health and Social Services
Division of Gastroenterology
McGill University Health Centre 

Educational Objectives: 
1. To gain an understanding of the determinants of QoL in adult IBD patients.
2. To gain an understanding of the cognitive and affective domains of the IBD illness experience
3. To gain an understanding of the applications of Positive Psychology as a tool to improve well- being in IBD 
Contact Person: Polymnia Galiatsatos, MD, Division of Gastroenterology, Tel. 514-340-8222 x 28144.

*November 26, 2018

WHAT'S METABOLIC SYNDROME

Mark Trifiro, MD
Professor of Medicine, McGill University 
Chief, Division of Endocrinology, Jewish General Hospital
Educational Objectives: 
1. Etiology of metabolic syndrome
2. Consequences and impact of metabolic syndrome 
Contact Person: Mark Trifiro, MD, Chief, Division of Endocrinology, Tel. 514-340-8222 ext. 23976.

*December 3, 2018

EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION (E-CPR) IN 2018: HOW, WHEN AND WHOM?

Martin Albert, MD, FRCPC, FACP
Internist-Intensivist, Hôpital du Sacré-Coeur de Montréal
Director of Intensive Care Program, University of Montreal
Clinical Professor, University of Montreal
Regular Researcher, HSCM Research Center
Intensivist, Montreal Heart Institute

Educational Objectives: 
1. Become aware of the growing use of extracorporeal cardiopulmonary resuscitation (E-CPR) for resuscitation in specific settings
2. Understand the basic principles of E-CPR
3. Identify patients who may be candidates for E-CPR
Contact Person: Paul Warshawsky, MD, Chief, Department of Adult Critical Care, Tel 514-340-7500.

*December 10, 2018

CROSSROADS BETWEEN MOOD SYMPTOMS AND AUTONOMIC DISTURBANCES IN ALPHA-SYNUCLEINOPATHIES

Chenjie Xia, MDCM, FRCPC 
Assistant Professor of Neurology and Neurosurgery
McGill University 
Neurologist
Jewish General Hospital 

Educational Objectives: 
1. Review mood symptoms and autonomic disturbances in alpha-synucleinopathies 
2. Discuss how the link between them may shed light on pathophysiology of mood disorders 
Contact Person: Jeffrey Minuk, MD, Chief, Department of Neurosciences, Tel. 514-340-8222 ext. 28770.

*December 17, 2018

UPDATE ON METASTATIC PROSTATE CANCER

Cristiano Ferrario, MD
Assistant Professor of Medicine, McGill University
Member, Division of Hemato-Oncology
Jewish General Hospital 

Educational Objectives: 
1. Review of current diagnosis of metastatic prostate cancer
2. Review of safety and efficacy of multiple treatment options currently available for metastatic prostate cancer 
Contact Person: Lawrence Panasci, MD, Division of Hemato-Oncology, Tel. 514-340-8248.

*January 7, 2019

POLYGENIC RISK SCORES TO PREDICT CLINICAL OUTCOMES

Brent Richards, MD
Professor of Medicine, McGill University 
Staff Member, Division of Endocrinology, Jewish General Hospital

Educational Objectives: 
1. To understand how genotypes from birth can be used to predict clinical outcomes later in life
2. To understand how to interpret a genetic risk prediction 
Contact Person: Mark Trifiro, MD, Chief, Division of Endocrinology, Tel. 514-340-8222 ext. 23976.

ºJanuary 14, 2019

Time to move on – from 9H to 4R: shorteR, safeR, cheapeR and betteR
Results of two randomized trials in adults and children, of 4 months Rifampin (4R) vs 9 months Isoniazid (9H) for treatment of latent TB

Richard Menzies, MD
Professor of Medicine, of Epidemiology and of Biostatistics , McGill University 
Associate Director of the McGill International TB Centre 
Member, Respiratory Division, MUHC Department of Medicine 

Educational Objectives:
1. To understand the potential risks and benefits of treatment of latent tuberculosis infection (LTBI)
2. To understand the potential advantages and disadvantages of different regimens for treatment of LTBI – in particular the current standard of 9 months INH (9H), and the new regimen of 4 months rifampin (4R) 
Contact Person: Karl Weiss, MD, Chief, Division of Infectious Diseases, Tel. 514-340-8222 ext. 22933.

*January 21, 2019

AN EPIDEMIOLOGICAL ANALYSIS OF THE MEDICAL LITERATURE: LESSONS LEARNED FROM AN ACCIDENTAL CAREER IN MEDICAL JOURNALISM

Christopher Labos, MDCM, MSc
Associate member, Office for Science and Society McGill University 
Contributor for the Montreal Gazette and CJAD 

Educational Objectives: 
1. To understand how issues of study design and analysis can affect the outcomes of clinical studies
2. To review how issues like confounding, bias, reverse causation, and random error lead us to misinterpret the findings of medical studies
3. To explore the common mistakes we make as both producers and consumers of scientific news 
Contact Person: Lawrence Rudski, MD, Chief, Division of Cardiology and Director, Azrieli Heart Center, Tel. 514-340-8222 ext. 22992.

*January 28, 2019

THIRTIETH ANNUAL HUMANIZATION OF CARE AWARENESS PROGRAM ROUNDS
KEEPING IT TOGETHER WHEN EVERYONE AROUND YOU IS FALLING APART
 

Susan Wener
Author, Therapist, Educator 

Educational Objectives: 
At the end of this lecture participants will be able to:
1. Understanding the importance of taking care of yourself while taking care of others
2. Learning to better use the resources available to you and within you
3. Understanding the patient-doctor and multidisciplinary team dynamic as a partnership
Contact Person: Ms. Rosamary Steinberg, Co-Chair, Humanization of Care Committee, Tel. 514-340-8222 ext. 25833.

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